Teen Patti brings together a world renowned mathematician Perci Tratchtenberg (Ben Kingsley) and Venkat (Amitabh Bachchan), a brilliant mathematician from India.
At a casino in London, the two geniuses meet. Venkat ignites Perci’s curiosity when he reveals that he has come across a theory that questions the existing principles of probability and randomness.
He decides to apply this discovery in the real world on Teen Patti (a poker game). Along with Shantanu (Madhavan), Sid (Siddharth Kher), Bikram (Dhruv Ganesh), Abbas (Vaibhav Talwar) and Aparna (Shraddha Kapoor) – he hits the gambling dens in Mumbai.
But brilliance comes with a price that threatens to destroy him.